With great difficulty and protracted follow up, I could extract this reply from mediafire team, which is self explanatory.
I am being flooded with mails and comments on "unable to download" issue. Please be patient, until "mediafire" set right its server problem. Hope we will have relief as early as possible.
hide details 11:41 PM (8 hours ago)
Thank you for contacting Mediafire. Our technical department has been hard at work isolating the exact cause for this error 22 continuing to occur with the Mediafire files. They have assured me at this point that once a file has been restored to working service, it will not go down again due to this particular error.
While this is normally an error that rarely occurs and our technical department is able to repair the error within a matter of a couple of hours of it being reported, this particular instance has been more difficult to isolate and repair. They should have this particular issue fully restored within a week as it is taking this amount of time for our back up servers to catch up with the updates considering the number of files we store. Once this has been completed we should no longer see these errors on our servers and have been able to implement a quick fix to repair any isolated incidences.
We value your membership and look forward to working with you in the future. Thank you for your patience in this matter. If there is anything we can assist you with please let us know.
The MediaFire Team